Establishment of experimental method for bone-conducted vibration elicited vestibular-evoked myogenic potentials in healthy guinea pigs
- VernacularTitle: 豚鼠骨导前庭诱发肌源性电位实验方法的建立及正常值测试
- Author:
Zichen CHEN
1
;
Juan HU
1
;
Yuzhong ZHANG
1
;
Xinyu WEI
1
;
Yongzhi YANG
2
;
Ying GAO
1
;
Yong XU
3
;
Ying CHENG
1
;
Feiyun CHEN
1
;
Min XU
1
;
Qing ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Vestibular evoked myogenic potentials; Bone conduction; Guinea pigs
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2018;53(12):939-943
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To estabilsh animal methods of bone-conducted vibration elicited cervical vestibular-evoked myogenic potentials (BCV-cVEMP) and ocular vestibular-evoked myogenic potentials (BCV-oVEMP) in healthy guinea pigs.
Methods:Eleven healthy (250-350 g) and awake guinea pigs were selected and undertake conventional BCV-cVEMP and BCV-oVEMP examination in prone position. Parameters of waveforms were cauculated.
Results:The BCV-cVEMP and BCV-oVEMP both could be elicited in 100% (22/22) in guinea pigs respectively, threshold was (85.5±10.8)dB SPL and (90.7±10.6)dB SPL for cVEMP and oVEMP; n1 latency was (4.5±1.3)ms and (4.3±1.5)ms for cVEMP and oVEMP; p1 latency was (5.8±1.4)ms and (5.6±1.7)ms respectively; n1-p1 interwave latency was (1.2±0.4)ms for cVEMP and (1.4±0.6)ms for oVEMP, amplitude was (21.5±17.3)μV and (24.0±16.3)μV respectively.
Conclusion:Both BCV-cVEMP and BCV-oVEMP can be successfully elicited in healthy guinea pigs.
