Progress of circulating tumor DNA detection in cancer

VernacularTitle: 外周血中循环肿瘤核酸检测的研究进展
Author: Ming ZHAO ¹ ; Kejing WANG ; Jinbiao SHANG ; Weihui ZHENG
Author Information

1. Department of Head and Neck Surgery, Zhejiang Tumor Hospital, Hangzhou, Zhejiang 310022, China
Publication Type:Journal Article
Keywords: DNA, Neoplasm; Blood circulation; Early detection of cancer; Review literature as topic
From: Chinese Journal of Primary Medicine and Pharmacy 2018;25(11):1495-1496
CountryChina
Language:Chinese
Abstract: Peripheral blood circulating tumor DNA(ctDNA) is a kind of DNA that is released into the blood circulation system after the tumor cell somatic cell DNA is exfoliated or when the cell apoptosis is released.ctDNA is a characteristic tumor biomarker, known as " liquid biopsy" . It can reflect the invasion and metastasis of the tumor, and can monitor the effect and prognosis of the tumor.The current research is mainly focused on relatively mature breast cancer, lung cancer and other diseases.In this study, the development of ctDNA inspection technology and its current research status at home and abroad are reviewed.