Effects of p-phenylenediamine on lung function and health-related quality of life of workers
10.3760/cma.j.issn.1001-9391.2018.11.009
- VernacularTitle: 对苯二胺对工人肺功能和健康相关生活质量的影响
- Author:
Ming ZHANG
1
;
Lin FAN
;
Baofeng LIU
;
Jing LIN
;
Huijing TANG
;
Baoli ZHU
;
Rongming MIAO
;
Xinglin FANG
;
Jiayang FANG
;
Shulang ZHAO
;
Meibian ZHANG
;
Qiang ZENG
Author Information
1. Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China
- Publication Type:Case Reports
- Keywords:
p-Phenylenediamine;
Occupational exposure;
Lung function
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2018;36(11):834-836
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects p-phenylenediamine (PPD) on lung function and health-related quality of life of occupational exposed workers.
Methods:This study was based on data from a company that produce hair dye containing PPD in China. Workers who exposed to PPD were selected as the study group, and workers un-exposed to PPD were selected as the control group. Questionnaires on health-related quality of life of workers using the 36-item Short Form Health Survey (SF-36) . Occupational health examination assessment results were tested in Taizhou Cancer Hospital. The lung function test includes forced vital capacity (FVC) , forced expiratory volume in one second (FEV1.0) , and ratio of FEV1.0 to FVC (FEV1.0/FVC) .
Results:The difference in systolic blood pressure between the PPD exposed group and the control group was statistically significant (P<0.05) . FVC, FEV1.0, and FEV1.0/FVC of the lung function indexes in the exposed group were lower than those in the control group (P<0.05) . In the health-related quality of life, body pain (P=0.002) , general health (P=0.029) , vitality (P=0.038) , and mental health (P=0.003) were lower in the exposed group than in the control group.
Conclusion:Occupational exposed to PPD may induce hazard to the workers’lung function and may cause detrimental effect on workers’ health-related quality of life.
