Research progress of circulating melanoma cells in melanoma
10.3760/cma.j.issn.1009-4598.2018.10.022
- VernacularTitle: 循环黑素瘤细胞在黑色素瘤中的研究进展
- Author:
Chuanyuan WEI
1
;
Jianying GU
Author Information
1. Department of Plastic Surgery, Zhongshan Hospital, Fudan University, Shanghai 20032, China
- Publication Type:Review
- Keywords:
Melanoma;
Circulating tumor cell
- From:
Chinese Journal of Plastic Surgery
2018;34(10):879-883
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the incidence of melanoma has increased rapidly worldwide. For the high malignancy and early metastasis of melanoma, many first-visit patients were diagnosed with distant metastasis and the tumor cannot be completely removed by surgery resection. Circulating melanoma cells are melanoma cells that enter the blood circulation from primary or metastatic lesions, playing an important role in tumor recurrence and metastasis. Previous studies have shown that testing for circulating melanoma cells by liquid biopsy can be used for early diagnosis, clinical staging, prognosis prediction and therapeutic evaluation, which have received extensive attention. This article reviewed the method of circulating melanoma cells detection and their related effects.
