Analysis on chromosome aberration rate, micronucleus cell rate and related factors of 3021 radiation workers in Changzhou
10.3760/cma.j.issn.1001-9391.2018.10.010
- VernacularTitle: 常州市3021例放射工作人员染色体畸变率和微核细胞率状况及影响因素分析
- Author:
Qiang FU
1
;
Guohai WANG
;
Qiang WANG
;
Jianquan ZHU
Author Information
1. Changzhou Center for Disease Control and Prevention, Changzhou 213022, China
- Publication Type:Case Reports
- Keywords:
Chromosome aberration rate;
Micronucleus cell rate;
Lonizing radiation
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2018;36(10):759-761
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the chromosomal aberration rate, micronucleus cell rate and the related factors of radiation workers in Changzhou, provide evidence for the occupational health and safety of radiation workers.
Methods:Descriptive analysis of the chromosomal aberration rate, micronucleus cell rate and the related factors of 3021 radiation workers who conducted occupational health examination in the Changzhou Center for Disease Control and prevention in 2017, multivariate logistic regression was used to analyze the data.
Results:The abnormal rate of chromosome aberration and micronucleus cells of 3021radiation workers in Changzhou were 1.32% and 3.34% respectively. The results of multivariate logistic regression showed that the exposure year (OR=1.501, 95%CI:1.078~2.089, P=0.016) was a risk factor for chromosome aberration. The risk of chromosome aberration in radiation therapy (OR=6.417, 95%CI:1.360~30.280, P=0.019) and interventional radiology (OR=4.598, 95%CI:1.688~12.524, P=0.003) was higher than that of industrial application. the exposure year (OR=1.245, 95%CI:1.007~1.539, P=0.043) is also a risk factor for micronucleus cell rate. The micronucleus cell rate abnormality Risk of nuclear medicine (OR=3.934, 95%CI:1.305~11.858, P=0.015) , radiation therapy (OR=3.802, 95%CI:1.101~13.128, P=0.035) , and interventional radiology (OR=2.953, 95%CI:1.324~6.584, P=0.008) is higher than industrial application.
Conclusion:The chromosome aberration rate and micronucleus rate of workers who are exposed to low dose ionizing radiation for long time are related to the exposure year of radiation workers and the occupational categories involved.
