Comparison of clinical value of total gastrectomy and proximal gastrectomy in the treatment of gastric fundus carcinoma
10.3760/cma.j.issn.1008-6706.2018.09.011
- VernacularTitle: 全胃切除与近端胃切除术治疗胃底癌的临床价值比较
- Author:
Hairong XIN
1
;
Yubao SONG
;
Longyue WANG
;
Zefeng GAO
Author Information
1. Department of General Surgery, Shanxi Tumor Hospital, Taiyuan, Shanxi 030013 China
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Gastrectomy;
Controlled clinical trial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(9):1130-1133
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical value of total gastrectomy and proximal gastrectomy in the treatment of gastric fundus carcinoma.
Methods:80 patients with gastric fundus cancer were divided into observation group and control group according to the random number method.The observation group was treated with total gastrectomy, and the control group was treated by proximal gastrectomy.The operation-related conditions, such as operation time, intraoperative bleeding and postoperative anal exhaust time of the two groups were compared.After surgery R0 resection rate and 2-year survival rate were analyzed.
Results:The operative time in the observation group was (86.3±1.9)min, which was shorter than (102.3±2.6)min in the control group (t=31.424, P<0.05). The intraoperative blood loss of the observation group was (180.5±15.0)mL, which was less than (230.0±25.0)mL of the control group (t=10.738, P<0.05). The anal exhaust time of the observation group was (41.5±2.1)h, which was shorter than (56.9±3.3)h of the control group (t=24.900, P<0.05). The percentage of pathologic R0 resection of the observation group was 32.5%(13/40), which was higher than 5.0%(2/40) of the control group (χ2=8.205, P<0.05). The 1-year survival rate and 2-year survival rate in the observation group were 92.5%, 67.5%, respectively, which were significantly higher than those in the control group(60.0%, 42.5%, χ2=4.943, 5.051, all P<0.05).
Conclusion:Compared with the proximal gastrectomy, the total gastrectomy in the treatment of gastric fundus carcinoma has shorter operation time, less intraoperative blood loss, quicker postoperative recovery, higher pathologic resection rate and survival rate.