Comparison of the effects of adaptive servo-ventilation and biphasic positive airway pressure in the treatment of adult heart failure patients complicated with complex sleep apnes syndrome
10.3760/cma.j.issn.1008-6706.2018.09.003
- VernacularTitle: 适应性伺服通气与双水平无创正压通气用于心力衰竭合并复杂性睡眠呼吸暂停综合征患者的效果比较
- Author:
Shuyi YU
1
Author Information
1. The Second Ward, the Second Hospital of Ninghai County, Zhejiang 315600, China
- Publication Type:Journal Article
- Keywords:
Ventilators, mechanical;
Sleep apnes syndromes;
Heart failure;
Controlled clinical trial
- From:
Chinese Journal of Primary Medicine and Pharmacy
2018;25(9):1099-1102
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the therapeutic outcomes of adaptive servo-ventilation (ASV) and biphasic positive airway pressure(BiPAP) in the treatment of adult chronic heart failure(CHF) patients complicated with complex sleep apnes syndrome(SAS).
Methods:34 adult CHF patients complicated with complex SAS were selected and divided into ASV group and BiPAP group according to random number table method, 17cases in each group.The clinical efficacy, polysomonograph(PSG) data and heart function during treatment were compared.
Results:The total effective rate of the ASV group was 88.2%(15/17), which was higher than 58.8%(10/17) of the BiPAP group(χ2=7.777, P<0.01). Compared with the BiPAP group, the sleeping efficacy, SpO2 and LVEF significantly increased in the ASV group (t=4.951, P<0.01; t=-5.743, P<0.01), while the AHI and CAI were significantly decreased in the ASV group (t=14.893, P<0.01; t=18.384, P<0.01). Compared with pre-treatment, the heart function parameters of the two groups after treatment were improved.Compared with the BiPAP group after treatment, the LVEF and 6min walking distance were significantly prolonged in the ASV group (t=-6.552, P<0.01; t=-6.720, P<0.01).
Conclusion:Compared with BiPAP, ASA showed better effect in the treatment of CHF patients complicated with complex SAS.It can improve the sleeping efficacy and respiratory disorder, decrease the AHI and CAI, and enhance the heart function, which is worth to be recommended into clinical application.