Combined treatment using cell scaffold and human fibroblast growth factor for small soft tissue defects of digits caused by trauma
10.3760/cma.j.issn.1009-4598.2018.09.010
- VernacularTitle: 细胞支架联合成纤维细胞生长因子修复手指急性创伤性软组织缺损
- Author:
Zhijin ZHANG
1
;
Linru ZENG
;
Jun YANG
;
Qiao HOU
;
Longfei LIU
Author Information
1. Xiaoshan Hospital of Traditional Chinese Medicine, Hangzhou 311201, China
- Publication Type:Journal Article
- Keywords:
Cell scaffold;
Fibroblast growth factor;
Finger, defect
- From:
Chinese Journal of Plastic Surgery
2018;34(9):729-732
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the effect of combined treatment using cell scaffold and human fibroblast growth factor for small soft tissue defects of digits caused by trauma.
Methods:From May 2012 to September 2016, twenty cases of small soft tissue defect of digits were repaired with cell scaffold combined with recombinant human basic fibroblast growth factor. The average defect area was 2.5 cm2. Wounds were debrided and repaired with artificial dermis. Every 2 or 3 days the dressings were changed and the wounds were treated externally with fibroblast growth factor until cell scaffolds have been removed 3-4 weeks after surgery.
Results:The group of 20 cases was followed up for 2-24 months. Wounds were healed with satisfactory appearance and no recurrence of wound or obvious hypertrophic scar was observed. No obvious functional problem was found in interphalangeal motion.
Conclusions:The method of repairing wound with cell scaffold combined with human fibroblast growth factor is simple and it result in healing of wounds with high quality.It provides a new choice for repairing wound in digits.
