Voxel-based morphometry (VBM) MRI analysis of gray matter in patients with occupational noise-induced hearing loss
10.3760/cma.j.issn.1001-9391.2018.09.008
- VernacularTitle: 职业性噪声聋患者脑灰质变化的VBM-MRI研究
- Author:
Aijie WANG
1
;
Chengkai CUI
;
Tiantao YE
;
Lianhong JIANG
;
Xiangrong CHEN
;
Guowei ZHANG
;
Yifang ZOU
Author Information
1. Yantaishan Hospital, Yantai 264001, China
- Publication Type:Case Reports
- Keywords:
Occupational Noise-induced Hearing Loss;
Voxel
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2018;36(9):677-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes of brain gray matter volume in patients with occupational noise-induced hearing loss by voxel based morphometry (VBM) .
Methods:16 age-and education-matched healthy controls and 42 patients with occupational noise induced hearing loss, including 27 in mild group and 15 in severe group, received MRI 3D-FSPGR sequence T1WI sagittal scan, and then underwent VBM of brain gray matter volume data analysis.
Results:The brain gray matter volume of the left occipitotemporal lateral gyrus, the anterior cingulate gyrus, the bilateral angular gyrus, the precuneus and the near midline area of cerebellum differed between experimental group and control group (P<0.01) .
Conclusion:The volume of gray matter in specific brain areas of patients with occupational noise-induced hearing loss was changed, and the effect of noise on brain structure was revealed from the perspective of imaging.