Ultrasonography-guided wire-localization and nano-carbon staining for detection of sentinel lymph node in breast cancer
10.3760/cma.j.issn.1006-9801.2018.08.007
- VernacularTitle: 超声造影导丝定位与纳米碳染色示踪探测乳腺癌前哨淋巴结的研究
- Author:
Xuye ZHAO
1
;
Weigang WANG
2
;
Yaling LI
3
;
Shuai LIANG
1
;
Nan ZHAO
4
;
Ailing LIU
5
;
Xiangyang GUO
1
;
Huijuan XU
1
;
Xia LI
6
;
Yanfeng XI
3
;
Xinzheng LI
1
;
Gaiqin XUE
4
Author Information
1. Department of Breast Surgery 2, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China
2. Department of Etiology, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China
3. Department of Pathology, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China
4. Department of Ultrasonography, Shanxi Provincial Cancer Hospital, Taiyuan 030013, China
5. Department of Ultrasonography, Hospital of Taishan Medical University, Taian 271000, China
6. Department of Oncology, Taiyuan Traditional Chinese Medicine Hospital, Taiyuan 030009, China
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Sentinel lymph node;
Ultrasound guided wire-localization;
Nano-carbon staining
- From:
Cancer Research and Clinic
2018;30(8):536-540
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the usage of ultrasound guided wire-localization, nano-carbon staining and the combination of the above two methods in detecting sentinel lymph node (SLN) in breast cancer.
Methods:A total of 159 cases of breast cancer from May 2015 to December 2017 in Shanxi Provincial Cancer Hospital were selected, and they were treated with ultrasound guided wire-localization, nano-carbon staining and combination of the two methods separately to detect SLN before the operation. After the operation, SLN and axillary lymph node in each group were marked and made pathological diagnosis.
Results:There were 69 cases with pathological diagnosis of SLN metastasis and 90 cases without abnormal representation. With the patient as the unit, the sensitivity of ultrasound guided wire-localization was 100.0% (69/69), the sensitivity of nano-carbon staining was 98.6% (68/69), and the sensitivity of combination of the two methods was 97.1% (67/69). The specificity of ultrasound guided wire-localization was 3.3% (3/90), the specificity of nano-carbon staining was 2.2% (2/90), and the specificity of combination of the two methods was 5.6% (5/90). With the count of SLN as the unit, the combination of the two methods had the highest diagnostic efficiency in detecting SLN, and the difference was statistical significant (χ2 = 34.31, P < 0.001).
Conclusions:Ultrasound guided wire-localization and nano-carbon staining are safe and accessible methods for detecting SLN. It provides a precise treatment for early breast cancer, and it can protect medical staff from radiation, which is expected to be the best method for detection of SLN in breast cancer.
