Progress of primary intestinal lymphoma
10.3760/cma.j.issn.1009-9921.2018.08.016
- VernacularTitle: 原发性肠道淋巴瘤的研究进展
- Author:
Fanfan ZHOU
1
;
Xin LI
;
Mingzhi ZHANG
Author Information
1. Department of Oncology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450002, China
- Publication Type:Review
- Keywords:
Gastrointestinal tract;
Lymphoma, B-cell;
Lymphoma, T-cell;
Prognosis
- From:
Journal of Leukemia & Lymphoma
2018;27(8):505-509
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of primary intestinal lymphoma (PIL) in primary gastrointestinal lymphoma (PGIL) is much lower than that of primary gastric lymphoma (PGL). Treatment strategies for PGL have been normalized, but there are still controversies concerning about the diagnosis criteria and optimal treatment of PIL. The lesions are mainly found in intestinal tract, and the most common involvement is ileocecal junction. The pathological types are derived from B-cell and diffuse large B-cell lymphoma (DLBCL) is the most common type, followed by extra-nodal marginal zone lymphoma of mucosa-associated lymphoid tissue. Surgery, chemotherapy, radiotherapy, antibiotics and monoclonal antibody therapy could be used as the monotherapy or different combined therapies, however, the final conclusion has not been reached in the treatment of PIL, accompanied by various influencing factors for prognosis. This review discusses the diagnosis criteria, clinical features, optimal treatment and prognostic factors of PIL. The diagnosis criteria and the optimal treatment will be put more emphasis.