Advances in the research of delivery system of growth factor and the gene for promoting wound healing
10.3760/cma.j.issn.1009-2587.2018.08.018
- VernacularTitle: 促进创面愈合的生长因子及其基因的递呈系统的研究进展
- Author:
Tong LIU
1
;
Haihang LI
;
Jiajun SHENG
;
Shihui ZHU
Author Information
1. Department of Burn Surgery, Institute of Burns, the First Affiliated Hospital, Naval Medical University, Shanghai 200433, China
- Publication Type:Review
- Keywords:
Drug carriers;
Genes;
Wound healing;
Growth factor
- From:
Chinese Journal of Burns
2018;34(8):566-569
- CountryChina
- Language:Chinese
-
Abstract:
Growth factors play critical roles in the process of wound healing. Application of growth factor locally is a good way of promoting wound healing, while it is easy to be hydrolyzed in wounds and its efficacy has dose- and time-dependent manner. Therefore, appropriate growth factor delivery system is needed to assist it to function in wounds. In addition to delivering growth factor directly to wounds, viral and non-viral vectors can be used for gene transfection of growth factor in wounds. The gene can be transformed to growth factor to promote wound healing by transcription and translation. This article reviews the advances in the research of delivery system of growth factor and the gene for promoting wound healing.
