Debridement combined with vacuum sealing drainage in the treatment of severe infection in abdominal wall due to allogeneic umbilical cord embedded in abdominal wall for immunotherapy
10.3760/cma.j.issn.1009-2587.2018.08.014
- VernacularTitle: 清创联合负压封闭引流治疗因腹壁包埋异体脐带行免疫治疗导致的腹壁严重感染
- Author:
Lianjie ZHANG
1
;
Chen WANG
;
Pengfei LUO
;
Tiansheng CHEN
;
Daofeng BEN
Author Information
1. Burn Institute of PLA, Department of Burn Surgery, the First Affiliated Hospital, Naval Medical University, Shanghai 200433, China
- Publication Type:Journal Article
- Keywords:
Umbilical cord;
Immunotherapy;
Debridement;
Negative-pressure wound therapy;
Abdominal infection
- From:
Chinese Journal of Burns
2018;34(8):556-558
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of debridement combined with vacuum sealing drainage (VSD) on the treatment of severe infection in abdominal wall due to allogeneic umbilical cord embedded in abdominal wall for immunotherapy.
Methods:From January 2015 to December 2016, 12 patients with severe infection in abdominal wall due to allogeneic umbilical cord embedded in abdominal wall for immunotherapy were admitted to our department. They were conducted with systemic anti-infective treatment, local debridement, and VSD. The wounds were continuously washed for 3 to 5 days after the VSD device installed, with negative pressure value from -16.0 to -12.0 kPa. The VSD device was removed 5 to 7 days later. Continue wound dressing by aseptic ribbon gauze was stuffed in the cavity, and the incision was sutured after the granulation tissue grew well in the cavity.
Results:In all patients, allogeneic umbilical cords were completely removed and abdominal infection was cured. The wounds healed well, the sensory function of abdominal was normal, and the activity was not restricted. All the patients were followed up for 3 to 6 months with no reinfection or incisional hernia.
Conclusions:Embeding the whole allogeneic umbilical cord in abdominal wall for immunotherapy can lead to severe infection in abdominal wall. Abdominal infection can be cured by debridement combined with VSD with good clinical results.
