Research progress of the clinical applications of tumor liquid biopsy
10.3760/cma.j.issn.1009-9158.2018.08.012
- VernacularTitle: 肿瘤液体活检临床应用的研究进展
- Author:
Wenrong JIANG
1
;
Hu ZHAO
;
Yanmei ZHANG
Author Information
1. Department of Laboratory Medicine, Huadong Hospital, Fudan University, Shanghai 200040, China
- Publication Type:Review
- Keywords:
Liquid biopsy;
Neoplastic cells, circulating;
Circulating tumor DNA;
Exosomes
- From:
Chinese Journal of Laboratory Medicine
2018;41(8):621-626
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, researches about liquid biopsies which contain circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and exosomes in the body fluids of patients with solid tumor have caused great concern. Compared with traditional biopsies, liquid biopsies have many advantages as they are real time, noninvasive and comprehensive. With the progress in the detecting techniques of CTC, ctDNA and exosomes, liquid biopsies can be applied to the early screening, diagnosis, treatment, prognostic evaluation of tumor. This review focuses on the recent advances in detection methods and clinical applications of CTC, ctDNA and exosomes.(Chin J Lab Med, 2018, 41: 621-626)
