Progress in the study of stem cell factor receptor c-kit in skin melanin metabolism
10.3760/cma.j.issn.1009-4598.2018.08.019
- VernacularTitle: 干细胞因子受体c-kit在皮肤黑色素代谢方面的研究进展
- Author:
Yu PING
1
;
Mo CAO
Author Information
1. Department of Plastic, Third Hospital of Hebei Medical University, Shijiazhuang 050051, China
- Publication Type:Review
- Keywords:
c-kit receptor;
Stem cell factor;
Melanocyte;
Skin;
Pigmentation
- From:
Chinese Journal of Plastic Surgery
2018;34(8):671-675,647
- CountryChina
- Language:Chinese
-
Abstract:
Skin melanin metabolism is a complex and fine regulation process, which is controlled by multiple genes, many enzymes and proteins. With the in-depth study of the factors affecting the skin melanin metabolism, scientists have found that the signaling pathway initiated by the combination of stem cell factor receptor c-kit and its ligand stem cell factor plays an important role in the metabolism of skin melanin.The paper summarizes the recent research progress on the role of c-kit receptor in the skin melanin metabolism, including the molecular mechanism and the clinical application.
