Therapeutic effect of 90Sr dynamic therapy in the treatment of pathological scar
10.3760/cma.j.issn.1009-4598.2018.08.013
- VernacularTitle: 90Sr同位素动态治疗在病理性瘢痕防治中的应用
- Author:
E YANG
1
;
Hengshu ZHANG
Author Information
1. The First Affiliated Hospital of Chongqing Medical University, Burn and Plastic Surgery, Chongqing 400016, China
- Publication Type:Journal Article
- Keywords:
Hypertrophic scar;
Keloid;
90Sr
- From:
Chinese Journal of Plastic Surgery
2018;34(8):640-643
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the therapeutic effect of surgery combined with 90Sr dynamic therapy used in pathological scar.
Methods:323 cases of pathological scar were treated with 90Sr dynamic therapy after surgery from June 2010 to June 2014. Initial treatment regimen was made according to the growth characteristics of pathological scar. Then adjusting the treatment programs according to the treatment response.The treatment effect and complications were compared between the new treatment regimen and traditional regimen used in 252 patients (June 2006 to May 2010). SPSS 17.0 was used for statistical analysis of data. Chi-square test was used for comparison of the differences between groups. The scars Vancouver scores were analyzed by one-way ANOVA two years after treatment. P<0.05 was considered statistically significant.
Results:The absorption rate in the proliferative phase of the dynamic treatment group was (4.32±0.00) cGy.s-1.cm-2, which was higher than that in the traditional treatment group (3.24±0.00) cGy.s-1.cm-2(F=1.742, P=0.000). Two years after treatment, the score in the dynamic treatment group was (2.94±1.22) points, which was lower than that in the traditional treatment group (4.21±1.68) (F=93.841, P=0.000); the complication rate and recurrence rate were 0.9% (3/323) and 0.6% (2/323) in dynamic treatment group while 11.1% (28/252) and 9.5% (24/252) in traditional treatment group, respectively. The difference was statistically significant(χ2=457.69, P=0.000; χ2=457.70, P=0.000).
Conclusions:The treatment of surgery combined with 90Sr isotope is effective in pathological scar, but treatment programs should be developed as a dynamic treatment according to the individual characteristics of the pathological scar.
