Application of DDI in prediction of fertility outcome after laparoscopic myomectomy
10.3760/cma.j.issn.0529-567x.2018.08.004
- VernacularTitle: DDI在预测子宫肌瘤剔除术后自然妊娠结局中的应用
- Author:
Xiuxiu LIANG
1
;
Zhenyu ZHANG
;
Chongdong LIU
;
Hong QU
Author Information
1. Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
- Publication Type:Clinical Trail
- Keywords:
Uterine neoplasms;
Leiomyoma;
Laparoscopy;
Pregnancy rate;
Pregnancy outcome;
Difficulty degree index
- From:
Chinese Journal of Obstetrics and Gynecology
2018;53(8):528-533
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the application of difficulty degree index (DDI) in predicting patients′s fertility outcome after laparoscopic myomectomy.
Methods:A retrospective study was carried out on 118 patients with subserous myoma or intramural myoma undergoing laparoscopic myomectomy from January 2005 to December 2014. The rate of post-operative pregnancy, delivery outcome and disease recurrence were investigated. Logistic regression analysis was used to analyze the impact of DDI, the age of patients undergoing surgery, presence of infertility history etc, on the patients′ reproductive outcome following the surgery.
Results:Follow-up for 1 to 10 years,118 cases were included in the study, the rate of post-operative pregnancy, live birth, vaginal delivery were 72.9% (86/118) , 52.5% (62/118) and 24.2% (15/62) respectively. No cases of uterine rupture and obstetric complications occurred. Univariate analysis showed that the independent variables of post-operative pregnancy rate were DDI, patient′s age at the time of surgery, presence of infertility history and myoma recurrence (all P<0.05) . In multivariate analysis, the factors of post-operative pregnancy rate were DDI (OR=3.131, 95%CI:1.012-8.894) , patient′s age at the time of surgery (OR=2.722, 95%CI:1.048-7.067) and presence of infertility history (OR=8.509, 95%CI: 2.102-34.445) .
Conclusions:DDI could be applied to predict post-operative pregnancy rate, with the increasing of DDI the post-operative pregnancy rate decreasing. The patients with high DDI scores, age>35 years old or presence of infertility history should get ready for pregnancy positively.
