Outcomes of severe primary fetal hydrothorax treated by prenatal intervention
10.3760/cma.j.issn.0529-567x.2018.08.003
- VernacularTitle: 重度原发性胸腔积液胎儿的宫内治疗及临床结局分析
- Author:
Bo XIA
1
;
Gang YU
;
Chun HONG
;
Pan YU
;
Jing WU
;
Jing TANG
;
Cuifen LIU
;
Huiwen YU
;
Wu MAO
;
Qianli LIU
Author Information
1. Department of Fetal Medicine, Guangdong Women and Children Hospital, Guangzhou 511440, China
- Publication Type:Clinical Trail
- Keywords:
Pleural effusion;
Fetal therapies;
Prognosis
- From:
Chinese Journal of Obstetrics and Gynecology
2018;53(8):522-527
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of intrauterine intervention on severe primary fetal hydrothorax.
Methods:Twelve cases with severe fetal primary hydrothorax who underwent prenatal intervention from January 2014 to December 2017 in Guangdong Women and Children Hospital were retrospectively reviewed.
Results:The median gestational age of prenatal diagnosis was 30.8 weeks (24.0-33.0 weeks) . All cases were excluded congenital chromosomal abnormalities by prenatal diagnosis, and had no complications of pregnancy during prenatal diagnosis and had hydrothorax. Three cases (3/12) were right hydrothorax, the other 9 cases (9/12) were bilateral. Thoracoamniotic shunting was performed in 7 cases (7/12) . Thoracentesis was performed in 5 cases (5/12) , and the hydrothorax reappeared soon after operation in 4 cases, shunt placement was performed again. The hydrothorax was dissolved in 2 cases, released in 6 cases.Tube falling off occurred in 1 case,treatment was abandoned in 1 case and intrauterine fetal death happened in 1 case, and 1 case wasn′t rechecked by ultrasonic due to premature birth following thoracentesis. In 10 cases who had deliveries, 5 newborns (5/10) were premature, 6 newborns (6/10) underwent assisted mechanical ventilation, 8 newborns (8/10) underwent thoracic close drainage, all of them were discharged when hydrothorax resolved.
Conclusions:Antenatal intervention may improve the chance of survival in severe primary fetal hydrothorax. Thoracoamniotic shunting is the first-choice for the primary severe fetal hydrothorax.