Two Cases of Gastric Mucosal Calcinosis.
- Author:
Ju Chun YEO
1
;
Dong Uk JU
;
Se Young LEE
;
Sung Woo EUM
;
Jai Hyun LEE
;
Se Hwan KIM
;
Chang Keun PARK
;
Seung Yup LEE
;
Hyun Soo KIM
;
Mi Jin KOO
Author Information
1. Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea. docyeo@hanmail.net
- Publication Type:Case Report
- Keywords:
Gastric mucosal calcinosis;
Bismuth;
Aluminum-containing antacids
- MeSH:
Antacids;
Biopsy;
Bismuth;
Calcinosis*;
Calcium;
Eating;
Endoscopy, Digestive System;
Follow-Up Studies;
Gastric Mucosa;
Gastritis;
Gastroesophageal Reflux;
Humans;
Hyperparathyroidism;
Renal Insufficiency;
Salts;
Stomach Neoplasms;
Sucralfate;
Transplants
- From:Korean Journal of Gastrointestinal Endoscopy
2006;33(4):230-234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gastric mucosal calcinosis (GMC) is a very rare condition that is characterized by the nodular deposition of calcium salts in the gastric mucosa. It has been associated with renal failure, gastric cancer, ingestion of aluminum- containing antacids and the use of sucralfate in organ transplant patients. The etiology of this condition is uncertain, but several theories have been proposed; the condition is due secondarily to hyperparathyroidism in renal failure and to the alkalinization of the gastric mucosa. We report here on two patients who had long-term use of bismuth and/or aluminum-containing antacids to treat their gastro-esophageal reflux symptoms. The esophagogastroduodenoscopy revealed acute gastritis patterns, and GMC was confirmed histologically with biopsy. When one patient stopped ingesting bismuth-containing antacid solution, the follow-up esophagogastroduodenoscopy and the biopsy revealed a completely improved state. We report here on these interesting cases and we include a brief review of the literature.
