Mitochondrial dysfunction and resuscitation in sepsis
10.3760/cma.j.issn.1673-4912.2018.07.007
- VernacularTitle: 脓毒症线粒体功能障碍及复苏
- Author:
Qi ZHANG
1
Author Information
1. Department of Pediatrics, China-Japan Friendship Hospital, Beijing 100029, China
- Publication Type:Journal Article
- Keywords:
Sepsis;
Mitochondrial dysfunction;
Mitochondria resuscitation
- From:
Chinese Pediatric Emergency Medicine
2018;25(7):507-512
- CountryChina
- Language:Chinese
-
Abstract:
Considering that the pathological changes are inconsistent with severe organ dysfunction of sepsis.It is urgent to explore the other pathogenetic mechanisms besides inflammation and immunity.A extraordinary explanation for multiple organ dysfunction is associated with mitochondrial dysfunction during sepsis.Although the exact relationship between them is not proved, and therapeutic strategy is suggested to promote the organs function by improving mitochondrial metabolism for sepsis.This article focused on mitochondrial biology, mitochondrial dysfunction, metabolic disorder and mitochondrial resuscitation in sepsis.
