Research progress in immunization status and immunization effect of preterm infants
10.3760/cma.j.issn.0253-9624.2018.07.017
- VernacularTitle: 早产儿免疫接种现状及疫苗免疫效果的研究进展
- Author:
Baozhen PENG
1
;
Jingxin LI
;
Yuanyuan ZHU
;
Fengcai ZHU
Author Information
1. School of Public Health, Southeast University, Nanjing 210009, China
- Publication Type:Review
- Keywords:
Infant premature;
Vaccination;
Immunization effect
- From:
Chinese Journal of Preventive Medicine
2018;52(7):762-768
- CountryChina
- Language:Chinese
-
Abstract:
Due to immature development of the immune system, preterm infants are at increased risk of infections from vaccine-preventable diseases. But at the same time, premature vaccination may not induce a good immune response because of the incomplete development of the neonatal immune system, and may cause serious adverse reactions risk due to the poor immune tolerance, thus vaccination of preterm infants at the appropriate time is the key to reducing the risk of infectious disease and obtaining vaccine protection. At present, it is generally recommended that the gestational age and birth weight should be considered in the vaccination of preterm infants. The timing, type and even the immunization schedule of the vaccine should be differ from that of the full term infants. However, there is a lack of research results and data on immunization program in preterm infants in China, and there is still no provided universal guidelines for their vaccine immunization. This article aims to summarize the guidelines and clinical trials of vaccination of preterm infants in foreign countries, and to provide reference for the formulation and implementation of immunization strategies for preterm infants in China.
