The value of protection device in microwave ablation at canine liver risk area
10.3760/cma.j.issn.1004-4477.2018.07.018
- VernacularTitle: 保护装置在犬肝脏风险区域微波消融中的价值
- Author:
Guangbin HE
1
;
Xiao LU
;
Dongyue GU
;
Qian YANG
;
Yue ZHANG
;
Haiying QIN
;
Xiaodong ZHOU
Author Information
1. Department of Ultrasound, the First Affiliated Hospital of Air Force Medical University, , Xi′an 710032, China
- Publication Type:Journal Article
- Keywords:
Microwave ablation;
Liver;
Diaphragm;
Artificialascites;
Dogs
- From:Chinese Journal of Ultrasonography
2018;27(7):630-635
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of protective device in microwave ablation at canine liver risk area, and the role of the device in reducing complications during ablation.
Methods:Six healthy mongrel dogs were randomly divided into two groups: group A, used protective devices; group B, unprotected. Conventional gray-scale ultrasound and contrast-enhanced ultrasound (CEUS) were performed before treatment to identify the ablation area (the right lobe of the liver near diaphragm, 1 cm from the surface of the liver). The two groups were treated percutaneous puncture liver microwave ablation under real time ultrasound-guided with the same ablation power (50 W) and equivalent ablation time (600 s). Liver specimens were evaluated histological examination to evaluate the necrotic area of ablation and the degree of diaphragm′s injury.
Results:①There was no significance difference in the ablation range between two groups[ (3.3±0.1)cm vs (3.5±0.1)cm, P=0.184]; ②The tolerance of group A was better than group B during ablation treatment; ③The mean maximum ablation diameter in group A was significantly lower than that in group B [(2.1±0.1)cm vs (5.3±0.2)cm, P=0.001]. Meanwhile the pathological results showed that the damage degree in group A was significantly lower than that in group B.
Conclusions:This protective device has an obvious protective effect for microwave ablation of the risk area in liver (adjacent diaphragm, hepatic envelope). Our experiment suggests that this protective can reduce the damage of adjacent organ and the complications during the ablation surgery.
