Quantitative assessment of renal tissue elasticity in patients with liver cirrhosis by shear wave elastography
10.3760/cma.j.issn.1004-4477.2018.07.013
- VernacularTitle: 应用剪切波弹性成像技术定量评价肝硬化患者肾组织弹性变化
- Author:
Huizhan LI
1
;
Tinghua FENG
;
Jiping XUE
;
Shuai LI
;
Ruiqing LI
;
Chunsong KANG
Author Information
1. Department of Ultrasound, Dayi Hospital of Shanxi Medical University, Taiyuan 030032, China
- Publication Type:Clinical Trail
- Keywords:
Ultrasonography;
Liver cirrhosis;
Kidney;
Shear wave elastrography
- From:Chinese Journal of Ultrasonography
2018;27(7):609-613
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the value of shear wave elastography (SWE) in the early diagnosis of hepatic cirrhosis nephropathy.
Methods:Seventy-three hepatic cirrhosis patients with normal conventional renal function were enrolled in the study, and were subdivided into Child-Pugh A group, Child-Pugh B group and Child-Pugh C group. Forty healthy volunteers were served as the control group. All the subjects underwent SWE to obtain the Young′s modulus value of left renal cortex, medulla and parenchyma which included Emax, Emin, Emean. The Young′s modulus value were compared among different groups.
Results:Compared to the control group, the Emax, Emean of left renal cortex, modulus and parenchyma in hepatic cirrhosis group were higher(P<0.05). Compared to the control group, there was no significant difference in Emax, Emin and Emean of left renal cortex, medulla and parenchyma in group A(P>0.05). The Emax and Emean of left renal cortex, medulla and parenchyma were higher both in group B and group C than those in control group(P<0.05). Comparison of liver cirrhosis among groups, the Emax and Emean of left renal cortex, medulla and parenchyma in group B and group C were higher than those of group A(P<0.05), there was no significant difference between group B and group C(P>0.05).
Conclusions:SWE can quantitatively determine the elastic parameters of renal tissue in patients with different degrees of cirrhosis, the change of renal tissue elasticity is earlier than that of routine laboratory examination, SWE can early detect renal tissue damage in patients with liver cirrhosis.
