The sonographic characteristics of papillary thyroid microcarcinoma and its risk evaluation of cervical lymphatic metastasis
10.3760/cma.j.issn.1004-4477.2018.07.011
- VernacularTitle: 甲状腺微小乳头状癌超声特征及其预测颈部淋巴结转移风险的价值
- Author:
Tong SUN
1
;
Jing TIAN
;
Na ZHUO
;
Chenyun LI
;
Qing DUAN
;
Jinyu SONG
;
Xuan BIAN
Author Information
1. Department of Ultrasound, the Second Hospital of Tianjin University, Tianjin 300211, China
- Publication Type:Clinical Trail
- Keywords:
Ultrasonography;
Thyroid neoplasms;
Lymphatic metastasis
- From:
Chinese Journal of Ultrasonography
2018;27(7):599-603
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the sonographic characteristics of papillary thyroid microcarcinoma(PTMC) and the preoperative prediction value for cervical lymphatic metastasis of PTMC.
Methods:Three hundred and fifty-eight PTMC patients who were confirmed by pathology and accepted partly or totally thyroidectomy and neck dissection were collected to analyze the sonographic characteristics, all patients were classified according to multifocal carcinoma nodules and solitary carcinoma nodules; cervical lymphatic metastasis or not; the maximum diameter of carcinoma nodules. Univariate analysis and Logistic regression analysis were used.
Results:Compared with solitary PTMC, multifocal PTMC was prone to emerge blood flow signals, heterogeneity, cervical lymphatic metastasis(all P<0.05). By univariate analysis, the risk factors of cervical lymphatic metastasis in PTMC were multifocal lesions and the total maximum diameter >1 cm, irregular edge, irregular shape, microcalcification, capsular invasion(all P<0.05). With Logistic regression analysis, the independent risk factors of cervical lymphatic metastasis in PTMC were multifocality and capsular invasion. Combining multifocality and capsular invasion, which area under the ROC(AUC) was 0.807.
Conclusions:Combining multifocality and capsular invasion significantly improves the risk of cervical lymphatic metastasis in PTMC by ultrasonography.
