Advances in the research of effects of exosomes on acute lung injury
10.3760/cma.j.issn.1009-2587.2018.07.011
- VernacularTitle: 外泌体在急性肺损伤中的作用研究进展
- Author:
Mingzhuo LIU
1
;
Chunxia GAN
;
Bin XU
;
Guanghua GUO
Author Information
1. Department of Burns, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China
- Publication Type:Review
- Keywords:
Exosomes;
Acute lung injury;
Stem cells
- From:
Chinese Journal of Burns
2018;34(7):481-485
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury (ALI) is a clinically common critical disease with various treatment methods. Stem cell has drawn great attention for excellent performance in treatment of ALI. However, due to its high apoptosis rate, the further clinical application of stem cell is restricted. Exosomes are a kind of extracellular vesicles secreted by cells, which play important role in injury repair with further research about exosomes. This article reviews current situation, brief introduction to exosomes, repair effects of exosomes on ALI, and the potential signal pathway.
