Goal-targeted therapy of inhalation injury with intratracheal delivery of drugs
10.3760/cma.j.issn.1009-2587.2018.07.005
- VernacularTitle: 吸入性损伤气道内给药目标靶向治疗
- Author:
Guanghua GUO
1
;
Wei SUN
Author Information
1. Department of Burns, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China
- Publication Type:Journal Article
- Keywords:
Burns, inhalation;
Intratracheal delivery of durgs;
Inhalation therapy;
Assisted ventilation;
Goal-targeted therapy
- From:
Chinese Journal of Burns
2018;34(7):445-449
- CountryChina
- Language:Chinese
-
Abstract:
Early airway management and respiratory support are essential for severe inhalation injury. Intratracheal delivery of drugs is better than other methods of administration, because of its higher local drug concentration, faster and more precise effect, and less systemic adverse reactions. It attracts more and more attention at present. In recent years, a growing number of drugs can be used in intratracheal delivery, in addition to common bronchodilators, mucolytics, and glucocorticoids, there are anti-inflammatory agents, antioxidants, and anticoagulants, etc. It is of great significance to improve the prognosis of patients with inhalation injuries with intratracheal delivery of drugs in goal-targeted therapy.
