Exosomes, the novel biomarkers, are being used in clinical examinations. When will they be available?
10.3760/cma.j.issn.1009-9158.2018.07.001
- VernacularTitle: "新宠"外泌体正式进入临床检验，路还有多远？
- Author:
Ping JI
1
;
Dong LI
Author Information
1. Department of Clinical Laboratory, Tongji Hospital of Tongji University, Shanghai 200065, China
- Publication Type:Editorial
- Keywords:
Exosomes;
Clinical laboratory techniques;
Liquid biopsy;
Biomarkers;
Reference standards
- From:
Chinese Journal of Laboratory Medicine
2018;41(7):487-490
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are nanovesicles secreted into the extracellular environment upon internal vesicle fusion with the cell membrane. A growing body of evidence suggests that exosomes may be used as biomarkers for the diagnosis and prognosis of malignant tumors and other pathologies. At present, the standardization of exosomes detection at home and abroad is still in primary stage. The consistency and accuracy of measurement results for exosomes are needed to be solved urgently. In the era of precision medicine, exosomes detection will continue to have significant impacts on laboratory medicine, in spite of the inherent challenges posed by the technology. This article reviews the exosomes detection development course and illustrates the challenges of appropriately applying exosomes detection to clinical diagnostics.(Chin J Lab Med, 2018, 41: 487-490)
