Review of the treatment for BRBNS by Sirolimus
10.3760/cma.j.issn.1009-4598.2018.07.020
- VernacularTitle: 西罗莫司治疗蓝色橡皮疱样痣综合征的临床研究进展
- Author:
Xu CHANG
1
;
Jianxun MA
;
Youchen XIA
Author Information
1. Peking University Third Hospital, Beijing 100191, China
- Publication Type:Review
- Keywords:
Sirolimus;
Vascular Malformation;
Blue rubber bleb nevus syndrome
- From:
Chinese Journal of Plastic Surgery
2018;34(7):574-577
- CountryChina
- Language:Chinese
-
Abstract:
Hemorrhagic anaemia caused by chronic gastrointestinal bleeding is a common complication of BRBNS that has the greatest impact on the patient′s quality of life, even life-threatening. Traditional treatments cannot slow down the overall progress of the disease. The curative effect is limited and has certain limitations. Sirolimus can effectively treat vascular malformations of the soft tissues, and it can control gastrointestinal lesions to correct iron deficiency anemia caused by bleeding, improve quality of life, and can inhibit disease progression and improve prognosis. This new emerging medication may become one of the powerful treatments for BRBNS in the future.
