Overview and clinical application in the 2017 World Health Organization classification of pituitary tumors

VernacularTitle: 2017年世界卫生组织垂体肿瘤病理分类变化及临床意义
Author: Xianxian YUAN ¹ ; Huijuan ZHU
Author Information

1. Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, The Translational Medicine Center of PUMCH, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China
Publication Type:Journal Article
Keywords: Tumors of the pituitary gland; Pathological classification; Clinical application
From: Chinese Journal of Endocrinology and Metabolism 2018;34(7):623-626
CountryChina
Language:Chinese
Abstract: The fourth edition of the World Health Organization classification of tumors of the pituitary gland was promulgated in 2017. The revised classification emphasized the classification of pituitary tumors based on the origin of cell differentiation. The term of atypical pituitary adenoma was no longer recommended, and morphological parameters should be considered as an important prognostic feature in aggressive adenomas. Genetic profile and susceptibility of pituitary tumors were updated. And an additional novel aspect was the definition of some of the nonneuroendocrine tumors. The revised classification will help the pathologists to make better diagnosis, and contribute to improve our understanding of clinical outcomes for those patients. (Chin J Endocrinol Metab, 2018, 34: 623-626)