Advances in epidemiology and serum markers for the noninvasive diagnosis of nonalcoholic fatty liver disease
10.3760/cma.j.issn.1007-3418.2018.06.020
- VernacularTitle: 非酒精性脂肪性肝病的流行病学与血清无创诊断研究进展
- Author:
Gong FENG
1
;
Na HE
2
;
Juning WANG
3
;
Man MI
1
;
Chunyan NIU
4
Author Information
1. Xi'an Medical University, Xi'an 710021, China
2. First affiliated Hospital of Xi'an Medical University, Xi’an 710077, China
3. Xi'an Peihua University, Xi'an 710125, China
4. Department of Gastroenterology, Xiangan Hospital Affiliated to Xiamen University, Xiamen 361101, China
- Publication Type:Review
- Keywords:
Fatty liver, alcoholic;
Epidemiology;
Alpha ketopamyl diacid;
Cytokeratin 18 fragment
- From:
Chinese Journal of Hepatology
2018;26(6):476-480
- CountryChina
- Language:Chinese
-
Abstract:
The global prevalence rate of nonalcoholic fatty liver disease (NAFLD) has increased year by year, and it has become the number one cause for chronic liver disease in China. In addition, the trend of NAFLD has become more pronounced and evident in female gender and younger age group. The long-term persistence of fatty liver disease may cause serious consequences. There are no accepted diagnostic criteria for diagnosing noninvasive diagnosis of NAFLD. Alpha-ketoglutarate is a newly discovered serological marker of high diagnostic value and considered the most valuable potential biomarker along with cytokeratine-18 (CK-18).
