Neonatal RICH associated with thrombocytopenia and coagulopathy: a case report and literature review
10.3760/cma.j.issn.1009-4598.2018.06.018
- VernacularTitle: RICH新生儿期出现血小板减少和凝血障碍一例报告并文献回顾
- Author:
Qingwen GAO
1
;
Weimin SHEN
;
Jun YAN
;
Haini CHEN
;
Yi JI
;
Jijun ZOU
;
Jianbing CHEN
;
Jie CUI
Author Information
1. Department of Burn-Plastic Surgery, Children′s Hospital of Nanjing Medical University, Nanjing 210008, China
- Publication Type:Review
- Keywords:
Rapidly involuting congenital hemangioma;
Thrombocytopenia;
Coagulopathy;
Kasabach-Merritt phenomenon
- From:
Chinese Journal of Plastic Surgery
2018;34(6):488-493
- CountryChina
- Language:Chinese
-
Abstract:
We treated a neonate who was diagnosed as rapidly involuting congenital hemangioma (RICH). With a review on the clinical manifestation, differential diagnosis, and treatment of RICH that associated with thrombocytopenia(TP)and coagulopathy(CP)and received platelet transfusions and embolization therapy including absolute ethanol and polidocanol in our hospital in March of 2015. The platelets and coagulation function soon returned to normal, the tumor involuted significantly. Surgical excision was proceeded subsequently. The platelets returned to normal level after a one-time platelet transfusion, meanwhile, multiple reexaminations of blood coagulation function were normal. Postoperatively, incision wound healed well. There was no recurrence, and the functional recovery of upper limb was satisfactory. RICH is a rare type of vascular tumor which may present with TP and CP similar to KHE-KMP in the neonatal period. More attention should be addressed to identify these two diseases, because the treatment and prognosis of which have significant differences. Consumption of coagulation factors with milder platelet decrease may also be a complication of slow flow venous or venolymphatic malformations.
