Analysis of 1019 cases with rabies exposure and prophylaxis
10.3760/cma.j.issn.1003-9279.2018.06.014
- VernacularTitle: 1 019例狂犬病暴露者预防处置现状分析
- Author:
Song YANG
1
;
Li LI
;
Fengting YU
;
Hui LI
;
Weili LI
;
Chengjie MA
;
Zaiyan LIANG
;
Siyuan YANG
;
Linghang WANG
Author Information
1. Department of Emergency Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 10015, China
- Publication Type:Journal Article
- Keywords:
Rabies;
Post-exposure prophylaxis;
Rabies vaccine;
Human rabies immunoglobulin
- From:
Chinese Journal of Experimental and Clinical Virology
2018;32(6):625-627
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the prophylaxis of population exposed to rabies, and provide a basis for prevention and control of rabies.
Methods:The registration data of 1 019 cases with rabies exposure in Beijing Ditan Hospital Affiliated to Capital Medical University from Mar, 2017 to Feb, 2018 were analyzed using the descriptive epidemiologic method.
Results:Among the 1 019 cases of rabies exposure, the sex ratio of men to women was 0.90∶1, with the highest proportion of them were between 26 and 46 years of age old, accounting for 46.5%. Rabies exposure reached its peak (46.9%) between June and September. In addition, 63.3% of the injuries were caused by dogs and 36.7% by cats. Most of the wounds (55.1%) occurred in hands; and the second was lower limbs (26.6%). Most of the cases (60.7%) had grade II wounds; followed by grade III wounds (39.1%); 69.3% of the cases completed immunization with rabies vaccine. In grade III exposure, 73.7% of the patients were immunized with rabies immunoglobulin. Most of the persons of grade III exposure (73.7%) received inoculation with human rabies immunoglobulin (HRIG).
Conclusions:Measures to control rabies should be focused on the management of dogs and cats and the standardization of rabies post-exposure prophylaxis.