State of the art and perspective of pulp regeneration
10.3760/cma.j.issn.1002-0098.2018.06.001
- VernacularTitle: 牙髓再生的研究现状与发展前景
- Author:
Junqi LING
1
;
J. Jeremy MAO
2
Author Information
1. Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University & Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
2. Center for Craniofacial Regeneration, Columbia University, New York, NY 10032, U S A
- Publication Type:Journal Article
- Keywords:
Pulp revascularization;
Stem cell transplantation;
Cell homing;
Tissue engineering;
Regenerative medicine
- From:
Chinese Journal of Stomatology
2018;53(6):361-366
- CountryChina
- Language:Chinese
-
Abstract:
Recently, various levels of success have been achieved in dental pulp and dentin regeneration using latest techniques such as pulp revascularization, stem cell transplantation and cell homing. These cutting-edge technologies utilize stem cell mobilization, homing and directional differentiation, stem cell sub-population isolation, expansion and transplantation, modification and optimization of biomaterials and/or synergetic effects of biological cues. The objective of this review is to identify approaches for clinical translation and improve the success rates of pulp regeneration. We will focus on either basic and clinical research progress of dental pulp revascularization, or translational challenges and strategies of stem cell transplantation and cell homing in dental pulp regeneration.
