Effects of occupational cadmium exposure on workers' cardiovascular system
10.3760/cma.j.issn.1001-9391.2018.06.025
- VernacularTitle: 职业镉接触对作业工人心血管系统的影响
- Author:
Zeren CAO
1
;
Shouming CUI
;
Xinxin LU
;
Xiaoman CHEN
;
Xuan YANG
;
Junpeng CUI
;
Guanghui ZHANG
Author Information
1. Xinxiang Academy of occupational health and occupational medicine, Xinxiang 453003, China
- Publication Type:Journal Article
- Keywords:
occupational cadmium exposure;
urinary cadmium;
hypertension;
ECG;
cardiovascular system
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2018;36(6):474-477
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of cadmium exposure on cardiovascular system of occupational workers.
Methods:Cross-sectional study was applied to 992 workers in a nickel-cadmium battery plant in November, 2011, of which 749 were cadmium exposed workers and 243 were controls without cadmium and other expose. Urinary cadmium、electrocardiogram (ECG) and blood pressure were examined simultaneously among 992 workers. The risk factors of ECG abnormality rate and hypertension rate were analyzed by Logistic regression.
Results:The level of urinary cadmium in cadmium exposed workers was significantly higher than controls (8.89±4.00 vs 1.34±1.18 μg/g creatinine, P<0.01) . Urinary cadmium level in women was significantly higher than men in both exposure and control group (P<0.05) . According to the group of working years, Urinary cadmium level raised with the increase of working years (F=28.272, P<0.001) . The ECG abnormality rate and hypertension rate of cadmium exposed workers were higher than that of control group, the differences were all statistically significant (P<0.01) . The abnormal rate of ECG and the hypertension rate increased with the prolonging of working years and demonstrated dose-response relationship. With the increase of urinary cadmium level, the abnormal rate of ECG and hypertension rate raised (OR=1.11, P<0.01) and (OR=1.15, P<0.01) respectively.
Conclusion:Occupational cadmium exposure increased the abnormal rate of ECG and blood pressure and therefore damaged cardiovascular system of workers. This study provided base data for protecting health of cadmium exposed workers.
