The relationship between smoking and hyperuricemia in Chinese residents
10.3760/cma.j.issn.0253-9624.2018.05.012
- VernacularTitle: 中国居民吸烟与高尿酸血症的相关性分析
- Author:
Henggui CHEN
1
;
Liting SHENG
;
Zhenzhen WAN
;
Xinchen WANG
;
Yuhui LIN
;
Yixin WANG
;
Xiongfei PAN
;
An PAN
Author Information
1. Department of Epidemiology and Biostatistics School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
- Publication Type:Journal Article
- Keywords:
Smoking;
Hyperuricemia;
Uric acid;
CHNS
- From:
Chinese Journal of Preventive Medicine
2018;52(5):524-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between smoking and hyperuricemia in Chinese residents.
Methods:Based on data from the China Health and Nutrition Survey (CHNS), residents with blood samples provided in the 2009 round (including information of socio-demographic factors, lifestyle behaviors, medical history, and laboratory examinations etc.) were selected as the participants in the current analysis. Unconditional logistic regression models were utilized to compute the ORs and corresponding 95%CIs for assessing the relationship between smoking and hyperuricemia.
Results:Among the 8 785 subjects, 1 435 had hyperuricemia with a prevalence rate of 16.3%, consisting of 886 men and 549 women with prevalence rates of 21.6% (886/4 110) and 11.7% (549/4 675) , respectively. Compared with never smokers, the adjusted OR (95%CI) for hyperuricemia was 0.83 (0.70-0.98) among current smokers, 0.77 (0.63-0.94) among current smokers with 20-39 years of smoking, and 0.79 (0.65-0.97) among current smokers with 11-20 cigarettes per day. When stratified by gender and compared with non-smoker, the adjusted OR (95%CI) for hyperuricemia among current smokers compared with never smokers was 0.83 (0.70-0.98) among men, while no significant association was found in female current smokers (OR=0.73, 95%CI: 0.42-1.26, P=0.260).
Conclusion:In Chinese residents, there is an inverse association between smoking and hyperuricemia prevalence, and this association may be related to duration and intensity of smoking among current smokers. The findings need to be validated in large prospective cohort studies.
