The clinical applications of nanofat for depressed scars treatment
10.3760/cma.j.issn.1009-4598.2018.05.012
- VernacularTitle: 纳米脂肪在凹陷性瘢痕治疗中的临床应用
- Author:
Hu JIAO
1
;
Jing PAN
;
Jincai FAN
;
Ran XIAO
;
Liqiang LIU
;
Cheng GAN
;
Zengjie YANG
Author Information
1. Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100144, China
- Publication Type:Journal Article
- Keywords:
Nanofat;
Autograft;
Depressed scar;
Fat granule injection grafting
- From:
Chinese Journal of Plastic Surgery
2018;34(5):375-378
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To treat the depressed scars by injecting nanofat and investigate its therapeutic effect.
Methods:Autologous fat was harvested from abdomen or thigh using low-pressure suction. The lipoaspirate was mechanically emulsified after rinsing. Emulsification of the fat was achieved by shifting the fat between two 5 ml syringes connected to each other by a three direct connector. After this emulsification process, the fatty liquid was again filtered over the sterile nylon cloth. Nanofat was injected into the dermis of depressed scars using a 26-gauge needle and the injection volume was 1-2 ml/cm2. After three months, another injection would be performed if the depressed scar remained obvious.
Results:From January 2016 to October 2017, eighteen patients and thirty-three depressed scars were treated. There was a temporary erythema of the injected area that lasted two to three weeks. The clinical result gradually improved over time and were maximal from three months postoperatively for most cases. Three months after nanofat injecting, the cavity of scars was significantly decreased; The color of scars were significantly improved and more close to the adjacent skin; The stiffness of scars was also obvious decreased. The follow-up ranged 4 months to 18 months and the average was 11.0±4.6 months. Seventeen patients were satisfied with the result, one patients was not satisfied and the satisfaction rate was 94%. No infections, fat cysts, granulomas, or other unwanted side effects were observed.
Conclusions:Nanofat injecting is a definite and effective treatment for depressed scars with fewer complications.
