Effect of radiotherapy for primary orbital lymphoma: analyses of 28 cases
10.3760/cma.j.issn.1009-9921.2018.04.012
- VernacularTitle: 原发眼眶淋巴瘤28例放疗效果分析
- Author:
Liuhua LONG
1
;
Peipei SUN
1
;
Dongrun TANG
2
;
Xinmin DING
3
;
Huaqing WANG
1
;
Wenhua ZHANG
1
;
Long ZHANG
1
;
Tai ZHANG
1
;
Fengwei WANG
1
Author Information
1. Department of Oncology, Tianjin Union Medical Center in Tianjin People's Hospital, Tianjin Cancer Institute of Integrated Traditional Chinese and Western Medicine, Tianjin 300121, China
2. Department of Ophthalmology, Tianjin First Central Hospital, Tianjin 300190, China
3. Department of Oncology, Tianjin Dagang Oil Company Hospital, Tianjin 300187, China
- Publication Type:Journal Article
- Keywords:
Orbital lymphoma;
Radiotherapy;
Drug therapy
- From:
Journal of Leukemia & Lymphoma
2018;27(4):243-245
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect and adverse reactions of radiotherapy in patients with primary orbital lymphoma.
Methods:A total of 28 patients with primary orbital lymphoma from Tianjin Union Medical Center, the First Central Hospital of Tianjin and Tianjin Dagang Oil Company Hospital between March 2006 and August 2012 were retrospectively analyzed. All the patients received orbital tumor dissection or biopsy, then received radiation therapy. Three patients received chemotherapy with CHOP protocol before radiotherapy. Radiotherapy was delivered routinely with 3D-conformal radiation therapy (CRT) technique with daily 2-2.5 Gy for 5 times per week and 3-5 fields. Total dosage was 20-50 Gy. There were 18 cases of 30 Gy, 1 case of 22 Gy, 1 case of 25 Gy, 1 case of 20 Gy, 1 case of 28.8 Gy, 3 cases of 40 Gy, 1 case of 42 Gy, 1 case of 46 Gy and 1 case of 50 Gy.
Results:All the patients had complete remission (CR) after radiotherapy during follow-up. One patient recurred after radiotherapy of 4 months and received CR with radiotherapy again. One patient died of lung infiltration. Acute complications during radiotherapy were conjunctivitis (28 cases, 100.0%) and keratitis (1 case, 3.6%), long-term complications with ophthalmoxerosis (10 cases, 35.7%) and decreased visual acuity (1 case, 3.6%).
Conclusion:Radiotherapy is an effective method for primary orbital lymphoma, and the adverse reactions can be tolerated for most patients.
