Laparoscopic type C1 hysterectomy based on the anatomic landmark of the uterus deep vein and its branches for cervical cancer
10.3760/cma.j.issn.0253-3766.2018.04.010
- VernacularTitle: 腹腔镜下以子宫深静脉及其属支为解剖学标志的C1型子宫切除术治疗宫颈癌的临床分析
- Author:
Meirong LIANG
1
;
Douxing HAN
2
;
Wei JIANG
3
;
Hui LIU
3
;
Ling LI
3
;
Meiling ZHONG
3
;
Lin LUO
4
;
Siyuan ZENG
1
Author Information
1. Medical College of Nanchang University, Nanchang 330006, China
2. Department of Nephrology, Jiangxi Provincial Children′s Hospital, Nanchang 330006, China
3. Department of Gynecologic Oncology, Jiangxi Maternal and Child Health Hospital, Nanchang 330006, China
4. Department of Pharmacy, Jiangxi Maternal and Child Health Hospital, Nanchang 330006, China
- Publication Type:Clinical Trail
- Keywords:
Cervical neoplasms;
Radical hysterectomy;
Pelvic autonomic nerve sparing;
Laparoscopy;
Prognosis
- From:
Chinese Journal of Oncology
2018;40(4):288-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To introduce the laparoscopic type C1 hysterectomy based on the anatomic landmark of the uterus deep vein and its branched and to evaluate its feasibility and safety for cervical cancer and its effect to bladder function and to provide some reference to simplify the surgical procedures of laparoscopic type C1 hysterectomy.
Methods:The clinicopathologic data of the patients with stage ⅠA2~ⅡB cervical cancer and who underwent the laparoscopic C1 hysterectomy based on anatomic landmark of the uterus deep vein and its branches between March 2010 and December 2015 was retrospectively analysed.
Results:A total of 99 patients received laparoscopic type C1 hysterectomy based on the anatomic landmark of the uterus deep vein and its branches, in which 93 patients reserved unilateral or bilateral pelvic autonomic nerve successfully, the other 6 patients were transfered to receive type C2 hysterectomy due to adhesions, bleeding or the low possibility of curative resection. The failure rate of the surgery was 6.1% (6/99). The average age of these 93 patients was 44.4±8.2 years (range 25~61 years) and there was one case of stage ⅠA2, 84 stage ⅠB1, 2 stage ⅠB2, 5 stage ⅡA1 and 1 stage ⅡB. The number of patients with squamous cell carcinoma was 67, adenocarcinoma was 19, adenosquamous carcinoma was 3, small cell neuroendocrine carcinoma was 3 and mixed type was 1. The average operation time was 4.1±0.5 h, the average amount of intraoperative blood loss was 103.8±84.0 ml and the mean number of excisional pelvic lymph nodes was 29.7±8.9. There was no patient with positive parametrial margin, positive vaginal margin or intraoperative ureteral injury. The postoperative catheter extraction time was 20.3±8.4 d. The median follow-up time was 20 months (rang 5~44 months), the long-term bladder dysfunction rate was 8.6% (8/93). The numbers of locally uncontrolled and distantly metastasis case were both one and both patients died. The fatality rate were 2.2% (2/93). The two-year disease-free survival and overall survival rate were 97.6% and 96.2%, respectively.
Conclusion:Laparoscopic type C1 hysterectomy based on the anatomic landmark of the uterus deep vein and its branches is a safe and feasible treatment method for cervical cancer and it provides a new approach for simplifying the surgical procedures of laparoscopic type C1 hysterectomy.
