Comparison of FibroTouch and FibroScan for the assessment of fibrosis in chronic hepatitis B patients
10.3760/cma.j.issn.1003-9279.2018.04.014
- VernacularTitle: FibroTouch和FibroScan检测评估慢性乙型肝炎患者肝纤维化程度的诊断价值
- Author:
Weijia DUAN
1
;
Xiaoming WANG
;
Yu WANG
;
Xinyan ZHAO
;
Xiaoning WU
;
Qianyi WANG
;
Jidong JIA
;
Xiaojuan OU
Author Information
1. Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
- Publication Type:Journal Article
- Keywords:
Chronic hepatitis B;
Fibrosis;
FibroTouch;
FibroScan
- From:
Chinese Journal of Experimental and Clinical Virology
2018;32(4):399-402
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the diagnostic values of FibroTouch and FibroScan for liver fibrosis in patients with chronic hepatitis B(CHB).
Methods:This study enrolled patients with CHB who was accepted liver biopsy at Beijing Friendship Hospital, Capital Medical University between March 2014 to December 2017. FibroTouch and FibroScan were performed among these patients at same time. Liver stiffness measurement(LSM), optimal cut-off value, receiver operating characteristic(ROC) were compared.
Results:In our 103 patients, there were no significantly different between FibroTouch and FibroScan in LSM. The threshold of the optimal cut-off value for FibroTouch and FibroScan were 5.45 versus 5.55 kPa (≥S1), 7.10 versus 6.65 kPa (≥S2), 11.05 versus 9.20 kPa (≥S3), 15.50 versus 15.45 kPa (S4), respectively. The area under the ROC curve for the prediction of the stage1, stage2, stage2, stage 4 of liver fibrosis in these patients were 0.858 versus 0.765 (P=0.54), 0.812 versus 0.801 (P=0.68), 0.863 versus 0.878 (P=0.45), and 1.0 versus 0.99 (P=0.38) respectively.
Conclusions:FibroTouch and FibmScan have a good consistency in the evaluation of the degree of liver fibrosis in patients with CHB.
