Simultaneous determination of various volatile organic compounds in urine by headspace GC-MS
10.3760/cma.j.issn.1001-9391.2018.04.019
- VernacularTitle: 顶空气相色谱-质谱法同时测定尿中多种挥发性有机物
- Author:
Yiran LIN
1
;
Tiandi LI
;
Fen LIU
;
Jianpei YUN
;
Yuxuan XIE
;
Jianhui CHEN
Author Information
1. Shenzhen Prevention and Treatment center for Occupational Diseases, Shenzhen 518001, China
- Publication Type:Journal Article
- Keywords:
Headspace;
GC-MS;
Urine;
Organic compounds
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2018;36(4):305-307
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for determination of acetone, dichloromethane, hexane, 1, 1, 1-trichloroethane, 1, 2-dichloroethane, benzene, toluene, ethylbenzene etc organic compounds in urine by headspace gas chromatography-mass spectrometry (GC-MS) .
Methods:Headspace gases of urine samples were injected into GC and determined by mass.
Results:Determination of urine components were in a good linear range in their concentration range of this method. The correlation coefficients were between 0.996 and 1.000 with the detection limits between 0.1 μg/L and 4.5 μg/L, the precisions were between 1.3% and 4.6%, the recovery rates were between 86.2% and 97.4%.
Conclusion:This method has the advantages of low detection limits, high accuracy, high precision and simple pretreatment, which is suitable for the determination of the content of various volatile organic compounds in urine.
