Study on bone metabolism in postmenopausal women with idiopathic benign paroxysmal positional vertigo
10.3760/cma.j.issn.1673-0860.2018.02.010
- VernacularTitle: 绝经后女性特发性良性阵发性位置性眩晕患者骨代谢的研究
- Author:
Chengyao GU
1
;
Weiwei HAN
2
;
Yunqin WU
1
;
Zhenyi FAN
1
;
Caijing CHEN
1
;
Huimin CHEN
1
Author Information
1. Department of Neurology, Ningbo No.2 Hospital, Ningbo 315010, China
2. Department of Rehabilitation, Ningbo No.2 Hospital, Ningbo 315010, China
- Publication Type:Journal Article
- Keywords:
Vertigo;
Bone density;
Osteocalcin;
Metabolism
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2018;53(2):134-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the bone mineral density and serum osteocalcin levels in postmenopausal women with idiopathic benign paroxysmal positional vertigo.
Methods:A total of 64 postmenopausal women with idiopathic BPPV were selected as the study group, and 98 postmenopausal healthy women were selected as the control group. Bone mineral density and serum osteocalcin levels were analyzed and compared between the groups.χ2 test was used for numeration data and t test was used for measurement data.
Results:The prevalence of osteoporosis or osteopenia in BPPV group 67.2% (43/64) was significantly higher than that in the control group 51.0% (50/98) (χ2=4.139, P=0.042). Among BPPV subjects, there was a negative correlation between osteocalcin and bone density T (r=-0.469, P<0.001). Osteocalcin was found in normal bone mass subgroup (13.61±4.32)μg/L, decreased bone mass subgroup (17.49±7.61)μg/L, and osteoporosis subgroup (20.83±6.72)μg/L, respectively, and the difference was statistically significant (F=5.39, P=0.007).
Conclusions:Bone mineral density in BPPV group is lower than that in control group. The lower the bone mineral density of the patients, the higher the osteocalcin in BPPV group.
