Analysis of curative effect of transoral radiofrequency ablation microsurgery on glottic carcinoma with anterior commissure involvement at the early stage
10.3760/cma.j.issn.1673-0860.2018.02.002
- VernacularTitle: 经口低温等离子手术治疗侵犯前连合的早期声门型喉癌
- Author:
Shuzhi YANG
1
;
Chengyong ZHOU
1
;
Feng WANG
1
;
Baochun SUN
1
;
Zeli HAN
1
;
Yao SHEN
1
;
Jiahong HAN
1
;
Hongjia ZHANG
1
Author Information
1. Department of Otorhinolaryngology, First Affiliated Hospital to the People Liberation Army General Hospital, Beijing 100048, China
- Publication Type:Journal Article
- Keywords:
Laryngeal neoplasms;
Anterior commissure;
Coblation;
Surgical procedures, minimally invasive
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2018;53(2):86-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the key technique and outcome of transoral radiofrequency ablation microsurgery for early stage of glottic carcinoma with anterior commissure involvement (ACI).
Methods:A retrospective analysis was conducted on 31 patients, who were diagnosed as early stage glottic carcinoma during January 2010 to March 2016 in ENT Department. According to whether the anterior commissure was involved or not, two groups were divided. There were eleven cases with ACI (stages T1a, T1b, and T2). Twenty cases without ACI (stages Tis, T1a, and T2). All the patients received transoral radiofrequency ablation microsurgery and followed up closely.Only one case received radiotheraphy after surgery. SPSS19.0 software was used to analyze data.
Results:The follow-up time was 12-67 months, and the median follow-up time was 30 months. Nine among 11 cases with ACI obtained good oncologic outcomes, initial local recurrence was identified in 2/11 cases, including 2 cases of T2. Two cases ultimately required salvage total laryngectomy. Meanwhile, initial local recurrence was identified in 2/20 cases without ACI, including 1 case of T1a and 1 case of T2. One case underwent elective neck dissection, and another one received salvage total laryngectomy.Compared to the patients without ACI, it seemed that the cases with ACI always accomponied with a little higher initial local recurrence and lower overall laryngealpreservation, but the difference had no significance (P>0.05).
Conclusions:Transoral radiofrequency ablation microsurgery is an effective treatment for glottic carcinoma with ACI. Its advantages, such as more flexibility and deformability, make it more feasible to operate at the narrow space of anterior commissure assisted with laryngeal endoscopy.Good oncologic outcomes can be obtained by this technique with lower initial local recurrence as well as higher overall laryngeal preservation rate.
