A review on mechanism and clinical implication of occult hepatitis B virus infection
10.3760/cma.j.issn.1003-9279.2018.02.025
- VernacularTitle: 隐匿性乙肝病毒感染发生机制和临床意义研究进展
- Author:
Wei LI
1
;
Wen WU
2
;
Xiangyan HUANG
2
Author Information
1. The Second Clinic, General Hospital of Jinan Military Command, Jinan 250002, China
2. Department of Blood Transfusion, General Hospital of Jinan Military Command, Jinan 250002, China
- Publication Type:Review
- Keywords:
Occult hepatitis B virus infection;
Occurrence mechanism;
Clinical significance
- From:
Chinese Journal of Experimental and Clinical Virology
2018;32(2):220-224
- CountryChina
- Language:Chinese
-
Abstract:
The level of viral DNA in patients with occult hepatitis B virus infection (OBI) is very low, and it is difficult to detect the conventional serum marker-HBsAg. OBI brought challenges to the clinical diagnosis and treatment and blood transfusion safety. The mechanism involved in OBI and the clinical implication are getting more and more attention. OBI has a complex mechanism that may involve host factors, the virus itself, and other viral or nonviral factors. OBI has the risk of HBV transmission. HBV can be reactivated and the liver disease can be aggravated in patients with OBI.
