Clinical analysis of children in hospital with adenovirus pneumonia in Beijing from 2015 to 2016
10.3760/cma.j.issn.1003-9279.2018.01.013
- VernacularTitle: 北京地区2015—2016年腺病毒肺炎住院儿童病例临床分析
- Author:
Mingyue LIU
1
;
Linying GUO
1
;
Dong QU
1
;
Jin ZHANG
1
;
Linqing ZHAO
2
;
Runan ZHU
2
;
Jie DENG
2
;
Fang WANG
2
;
Yu SUN
2
Author Information
1. Department of Intensive Care Unit, Capital Institute of Pediatrics, Beijing 100020, China
2. Virology Laboratory, Capital Institute of Pediatrics, Beijing 100020, China
- Publication Type:Journal Article
- Keywords:
Adenovirus pneumonia;
Child;
Clinical features
- From:
Chinese Journal of Experimental and Clinical Virology
2018;32(1):62-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical characteristics of children with adenovirus pneumonia and provide evidence for clinical diagnosis and treatment timely.
Method:This retrospective study included 89 children who were confirmed to have adenovirus pneumonia in hospital from January 2015 to December 2016. All the immunofluorescence test result of the 89 children showed that the exfoliated nasopharyngeal cells from the 89 children were all adenovirus antigen positive. All the severe type children reached the diagnostic criteria of severe pneumonia by the respiratory group in the society of pediatrics, Chinese Medical Association. The children were divided into 2 groups (severe type group and common type group). Different factors such as epidemiologic feature, clinical manifestation, laboratory examination and imaging data were analyzed.
Results:Among the 89 pediatric patients, the male to female ratio was 1.5∶1. The ages ranged from 1 month to 14 years. Children under 5 years of age accounted for 96.6%(86/89). The incidence was 37.1%(33/89)in winter and 30.3%(27/89)in spring. The lengths of hospital stay were 3-48 days and the median length of stay was 8.25±4.75 days. All of these 89 cases had fever and cough. The proportion of severe adenovirus pneumonia was high among male, under 2 years of age, those with dyspnea, hepatosplenomegaly, tachycardia, leukocytosis, elevated C-reactive protein (CRP), PCT, myocardial enzymes, electrocardiogram abnormality and cluster shadow in chest CT. Differences were statistically significant (P<0.05).
Conclusions:Special attention should be paid to the male children under the 2 years of age with abnormal related indicators to consider severe adenovirus pneumonia. Early detection and treatment are the key to improve treatment and reduce death.
