Molecular characteristics of norovirus in 4 outbreaks of gastroenteritis in Heilongjiang province in 2016
10.3760/cma.j.issn.1003-9279.2018.01.012
- VernacularTitle: 黑龙江省2016年4起胃肠炎暴发中诺如病毒分子特征分析
- Author:
Jun XU
1
;
Xin SHI
1
;
Chang SHU
1
;
Yan LENG
2
;
Bo CAO
1
;
Wei SUN
1
Author Information
1. Heilongjiang Provincial Center for Disease Control and Prevention, Harbin 150030, China
2. Jixi Municipal Center for Disease Control and Prevention, Jixi 158100, China
- Publication Type:Journal Article
- Keywords:
Norovirus;
Outbreaks;
Genotype
- From:
Chinese Journal of Experimental and Clinical Virology
2018;32(1):57-61
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the molecular characteristics of norovirus in 4 outbreaks of gastroenteritis in Heilongjiang province in 2016.
Methods:Fecal specimens of patients were collected from 4 outbreaks of acute viral gastroenteritis. Real-time PCR was performed to identify the infection with Norovirus (NoV). The NoV genes were amplified and sequenced for the positive samples, followed by performing phylogenetic analysis.
Results:There were total 4 outbreaks of viral gastroenteritis caused by NoV. A total of 102 stool specimens were obtained from cases with acute gastroenteritis. NoV was detected in 35 cases including 14 strains of genogroup I NoV and 21 strains of genogroup II NoV. Six genotypes including GII.2, GII.17, GII.Pe, GII.P12/GII.3, GI.6, GI.Pd/GI.3 were detected.
Conclusions:NoV was the pathogen causing the gastroenteritis outbreaks in Heilongjiang province, and multigenotype NoV co-circulated in Heilongjiang province.
