Seroepidemiology of H. pylori Infection in Normal Preschool Children.
- Author:
Yon Ho CHOE
1
;
Eui Chong KIM
;
Jeong Kee SEO
Author Information
1. Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Helicobacter pylori;
Prevalence;
Preschool children;
IgG GAP test
- MeSH:
Child;
Child, Preschool*;
Helicobacter pylori;
Humans;
Immunoglobulin G;
Korea;
Prevalence;
Seoul
- From:Korean Journal of Pediatric Gastroenterology and Nutrition
1999;2(2):147-152
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to evaluate the prevalence of H. pylori infection in normal preschool children. METHODS: Study population consisted of 220 preschool children aged 2 to 5 years in Seoul, Korea. We measured H. pylori specific IgG antibody using the GAP test IgG kit, and samples with concentrations greater than 20 U/ml were considered positive. RESULTS: Of the 220 children, 5 (2.3%) were positive, and thirteen (5.9%) of 220 were equivocally probable positive. CONCLUSION: The positive rate of H. pylori infection detected by specific IgG antibody in normal preschool children aged 2 to 5 years was approximately 2.3% to 8.2%. This prevalence rate is still high, compared to that of the West. A better knowledge of the transmission of H. pylori is crucial to formulate recommendations for lowering the rate.
