Application of stereotactic body radiation therapy in advanced renal cell carcinoma
10.3760/cma.j.issn.1673-422X.2019.10.013
- VernacularTitle: 立体定向体部放疗在晚期肾癌治疗中的应用
- Author:
Liang CAI
1
;
Yali SHEN
2
Author Information
1. Lung Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China
2. Department of Abdominal Oncology, West China Hospital, Sichuan University, Chengdu 610041, China
- Publication Type:Review
- Keywords:
Kidney neoplasms;
Advanced tumor;
Stereotactic body radiation therapy
- From:
Journal of International Oncology
2019;46(10):627-630
- CountryChina
- Language:Chinese
-
Abstract:
Stereotactic body radiation therapy (SBRT) can effectively kill renal cancer cells by biological molecules such as hypoxia-inducible factor-1α and acid sphingomyelinase. SBRT regimen with higher biological dose and single irradiation can achieve more effective local control of primary and metastatic lesion of advanced renal cancer, and adverse reactions can be tolerated. Combination of SBRT and targeted drugs can increase the sensitivity of renal cancer to radiotherapy, and the combination of SBRT and immune drugs can enhance the immune response through the abscopal effect. The efficacy of SBRT in the treatment of advanced renal cancer remains to be explored.
