Expression of miR-490 in malignant tumors and its molecular mechanism
10.3760/cma.j.issn.1673-422X.2019.10.006
- VernacularTitle: miR-490在恶性肿瘤中的表达及其分子机制
- Author:
Siyuan DENG
1
,
2
;
De HE
3
Author Information
1. Postgraduate College of Guangdong Medical University, Zhanjiang 524023, China
2. Shenzhen Bao′an Clinical Medical College of Guangdong Medical University, Shenzhen 518101, China
3. Shenzhen Bao′an Clinical Medical College of Guangdong Medical University, Shenzhen 518101, China
- Publication Type:Review
- Keywords:
MicroRNAs;
Neoplams;
Gene expression;
Mechanism;
miR-490
- From:
Journal of International Oncology
2019;46(10):601-604
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA-490 (miR-490) is an important member of the miRNA family and is closely related to the occurrence and development of tumors. Studies have shown that miR-490 is abnormally expressed in various tumors such as gastric cancer, colorectal cancer, breast cancer, etc., which plays an oncogene or tumor suppressor gene role in the biological behaviors such as proliferation, apoptosis, invasion and metastasis of different tumor cells. MiR-490 is expected to be an indicator of tumor diagnosis and clinical prognosis, and in-depth study of its mechanism is expected to provide a new direction for the diagnosis and treatment of cancer.
