MicroRNAs and diffuse large B cell lymphoma
10.3760/cma.j.issn.1673-422X.2019.09.012
- VernacularTitle: 微小RNA与弥漫大B细胞淋巴瘤
- Author:
Ye SUN
1
;
Lixia SHENG
2
;
Guifang OUYANG
2
Author Information
1. Department of Clinical Medicine, Medical School of Ningbo University, Ningbo 315211, China
2. Department of Hematology, Ningbo First Hospital, Ningbo 315000, China
- Publication Type:Review
- Keywords:
Lymphoma, large B-cell, diffuse;
MicroRNAs;
B-lymphocytes;
Diagnosis;
Prognosis
- From:
Journal of International Oncology
2019;46(9):566-569
- CountryChina
- Language:Chinese
-
Abstract:
The molecular mechanism of diffuse large B cell lymphoma (DLBCL) has not been fully elucidated, and epigenetics plays an important role in its development. MicroRNAs (miRNAs) are important parts of epigenetics, which are involved in the occurrence and development of DLBCL. Relevant studies have found that miRNAs can not only be used as molecular diagnostic markers of DLBCL, but also be used to judge the prognosis and treatment effect of DLBCL.