Advancement of the risk prediction of hepatocellular carcinoma in patients with chronic hepatitis B virus infection
10.3760/cma.j.issn.1673-422X.2019.09.010
- VernacularTitle: 慢性乙型肝炎病毒感染患者发生肝细胞肝癌风险预测的研究进展
- Author:
Wenjun CHEN
1
;
Junjuan WANG
2
;
Jianni QI
;
Chonghai DONG
1
;
Chengyong QIN
3
Author Information
1. Department of Gastroenterology, Affiliated Weihai Second Municipal Hospital of Qingdao University, Weihai 264200, China
2. Department of Child Rehabilition, Affiliated Weihai Second Municipal Hospital of Qingdao University, Weihai 264200, China
3. Department of Central Laboratory, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China
- Publication Type:Review
- Keywords:
Hepatitis B virus;
Infection;
Carcinoma, hepatocellular;
Risk assessment
- From:
Journal of International Oncology
2019;46(9):558-561
- CountryChina
- Language:Chinese
-
Abstract:
It is of important significant to predict the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus infection in clinic. Various risks scoring systems can achieve better prediction effect by integrating a variety of risk factors, but they still need to be perfected. Recent researches have found that some genotypes and genetic variations are associated with the occurrence of HCC and they can indicate the tumorigenesis of HCC. Some known or newly discovered indicators such as WFA+ -M2BP can be used to predict the occurrence of HCC independently or jointly. With the development of research, more genes, indicators as well as newly built scoring system will be utilized to predict the occurrence of HCC in clinic.
